PROFESS

Release 1.5
(2013-08-25)






StatsDatabase Statistics

Function

eggNOG Clusters 224,847
Enzyme Classes 5,093
GO Terms 27,606
Ligands 9,330
PFAM 10,340
Protein Interactions 67,113

Evolution

Essential Genes 6,099

Structure

CATH Classes 2,178
Protein Structures 56,699
Structure Comparisons 401,967

Sequence

Protein Sequences 10,891,633

Disease

Pancreatic cancer 2,013

Other

Taxonomy 558,282
Last update: 2013-08-25

TeamDevelopment Team

Contact:    Thomas Triplet


Database Design and Programming
Peter Revesz
Thomas Triplet


Genomics
Mark A. Griep
Robert Powers
Matthew D. Shortridge
Jaime Stark

PROFESS is a biology database system that integrates databases describing PROtein Functions, Evolution, Structures and Sequences. PROFESS aims at assisting researchers in the functional and evolutionary analysis of the abundant number of novel proteins continually identified from whole-genome sequencing. Read more...




Latest News

06/06/2010
PROFESS has been published in the journal Database. Full-text article is available open-source online.


04/10/2010
The BLAST search has been improved. You can now visualize the ouput from BLAST and select relevant protein sequences to further query PROFESS.


03/30/2010
Release 1.5 now includes sequences from Swiss-PROT and TrEMBL from UniProt. This major update also includes eggNOG, which replaces the older COG/KOG database and significantly increases the number of orthologous clusters.


02/21/2010
Release 1.2 enables BLASTP queries against sequences within PROFESS. BLAST queries are available on the Advanced Search page.


08/12/2009
The Database of Essential Genes and the Database of Interacting Proteins are now part of PROFESS 1.1.


04/23/2009
Release of PROFESS 1.0, which integrates CATH, COG, EC, Essential Genes in E. coli, GO, KEGG Ligands, PDB, PFAM, Protein/Protein interactions in E. coli and UniProtKB Taxonomy. If you would like a specific database to be integrated within PROFESS, contact us!


04/07/2009
First public release of PROFESS 0.7 (beta). Note this version is still under development and some features are missing. Please help us to improve the system by sending us your feedback and comments.


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