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Thursday, October 1, 2015 Talk:
4:00 p.m. - 5:00 p.m., Avery Hall 115
Reception:
3:30-4:00 p.m., 348 Avery Hall
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Dong Xu, Ph.D. - Distinguished Speaker
James C. Dowell Professor and Chair, University of Missouri-ColumbiaAbstract
Emerging biomedical big data provide unique opportunities for new hypothesis generation and translational research, especially precision medicine.
In this talk, I will illustrate some of our sample applications of using big data knowledgebase and analytics in biomedical research: (1) Soybean Knowledge Base (SoyKB, http://soykb.org), a comprehensive web resource for data analytics, hypothesis generation, and molecular breeding of soybeans; (2) MUFOLD-CL (http://mufold.org/clustering.php), a fast clustering method for large-scale protein structural models and other biomedical data; (3) usage of large-scale genomic data for clinical diagnosis; (4) a decision support system for personalized medicine according to individual patient data; and (5) a household-level health App based on traditional Chinese medicine. These applications show different dimensions of big data impact and challenges in biomedical research.
Speaker Bio
Dong Xu is James C. Dowell Professor and Chair of Computer Science Department, with appointments in the Christopher S. Bond Life Sciences Center and the Informatics Institute at the University of Missouri-Columbia. He obtained his PhD from the University of Illinois, Urbana-Champaign in 1995 and did two years of postdoctoral work at the US National Cancer Institute. He was a Staff Scientist at Oak Ridge National Laboratory until 2003 before joining the University of Missouri. His research includes protein structure prediction, high-throughput biological data analyses, in silico studies of plants, microbes and cancers, and mobile App development for healthcare. He has published more than 260 papers. He is a recipient of 2001 R&D 100 Award, 2003 Federal Laboratory Consortium’s Award of Excellence in Technology Transfer, and 2010 Outstanding Achievement Award from International Society of Intelligent Biological Medicine. He is Associate Editor-in-Chief of “IEEE/ACM Transactions on Computational Biology and Bioinformatics.”